Why an IVF Cycle FailsOne reason an IVF cycle fails. When we are defining failure as having no pregnancy at the end of the fertility treatment cycle, it's any IVF cycle that does not create a viable pregnancy.  It's a hard term, failure. But the measure of success in a fertility treatment cycle is an on-going, healthy pregnancy, so unfortunately the term failure fits better than we would like.

1 Reason for IVF FailureWhy Does an IVF Cycle Fail?

There are many benchmarks that can be pointed to as the reason that an IVF cycle does not work. Medication stimulation may not be effective and no eggs are produced or are able to be retrieved. Eggs are retrieved and do not fertilize. Male factor may play it's part and there are not healthy enough sperm to make embryos. The embryo cells may not continue to divide and so the embryo is not able to be transferred back to the uterus. These are just among a few of the reasons that a pregnancy does not occur or is not sustained.

Aneuploidy - A Cause of an Unsuccessful IVF Cycle

One thing that is understood to be one of the most common reasons for IVF failure and early miscarriage, is aneuploidy.

Aneuploidy is the term used to describe any embryo with either too many or too few chromosomes. Most people are not aware that aneuploidy is the cause of greater than 60% of miscarriages, as well as the most likely reason that patients do not get pregnant from an in-vitro fertilization (IVF) cycle.

Euploidy describes an embryo with the correct amount of chromosomes.

Pre genetic screening genetic screening is a valuable tool that is used to check for the efficacy of an embryo. Ask your fertility doctor (board certified Reproductive Endocrinologist) about whether that would be a helpful step for you in building your family.

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Topics: Miscarriage, In Vitro Fertilization (IVF)

Lisa Rosenthal

Lisa has over thirty years of experience in the fertility field. After her personal infertility journey, she felt dissatisfied with the lack of comprehensive services available to support her. She was determined to help others undergoing fertility treatment. Lisa has been with RMACT for eleven years and serves as Patient Advocate and the Strategic Content Lead.

Lisa is the teacher and founder of Fertile Yoga, a program designed to support men and women on their quest for their families through gentle movement and meditation.

Lisa’s true passion is supporting patients getting into treatment, being able to stay in treatment and staying whole and complete throughout the process. Lisa is also a Certified Grief Recovery Specialist, which is helpful in her work with fertility patients.

Her experience also includes working with RESOLVE: The National Infertility Association and The American Fertility Association (now Path2Parenthood), where she was Educational Coordinator, Conference Director and Assistant Executive Director.

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